In-office use of sodium fluorescein (NaFl) with hybrid lenses has historically been restricted to high-molecular-weight formulations to avoid discoloration of the HEMA soft lens component of older designs. By applying normal NaFl on the ocular or contact lens surface and by using a cobalt blue filter, many clinical observations can be made regarding the fit of today’s hybrid lenses.
Sodium Fluorescein Use
During Fitting If a diagnostic lens set is used for a hybrid lens fit, it is likely to assess the vault of the hybrid lens over an irregular corneal surface, similar to a scleral lens fit assessment. NaFl instilled into the bowl of a trial hybrid lens filled with preservative-free saline is applied on eye and evaluated within the first few minutes. The tear chamber above the corneal apex of a vault-based hybrid lens should be about half the thickness of the GP portion of the lens (Figure 1). Fluorescein can also be placed on the surface of the lens to accentuate the thickness of the GP center for evaluation purposes.
During Initial Dispense Empirically fit hybrid lenses for regular corneas, in which the GP center masks any underlying corneal astigmatism, are typically observed without the aid of NaFl. Predicted base curve calculations, in conjunction with an expected dioptric range for over-refraction, are markers for adequacy of fit. If NaFl is applied to the front surface of a hybrid lens that is fit on a regular spherical or astigmatic cornea, expect to see NaFl creep under the lens surface within the first minute of wear to highlight adequate tear exchange upon blink and a mobile lens. With fluorescein diluted in the layer of tears between the back of the lens and the front of the cornea, you will see a thin characteristic layer of NaFl under the GP center and a more intense NaFl ring at the GP/soft skirt junction corresponding to the clearance of the hybrid lens over the cornea (Figure 2).
During Follow up At follow-up visits, when evaluating the integrity of the cornea and conjunctiva, look for signs of a tight lens fit and seal off of the soft skirt and/or GP portion of the lens on eye (Figure 3). When tears become stagnant beneath the adhered hybrid lens, hyper-fluorescence of particles on the surface of the cornea can be observed; this confirms that a change in the skirt curve or base curve is warranted to loosen the lens fit and to promote adequate tear exchange. CLS