Clinical Report: Corneal Sensitivity and GP Lenses
Overview
Expand on the multifactorial aspects of lens comfort and the specific role of corneal sensitivity.
Background
Corneal sensitivity is a critical factor influencing the comfort of GP lens wear, especially in patients with keratoconus. Understanding the interplay of corneal sensitivity, lens fit, and patient anxiety is essential for optimizing lens fitting and improving patient outcomes. This topic is particularly relevant given the increasing use of GP lenses in managing keratoconus and the challenges associated with fitting these lenses in sensitive patients.
Data Highlights
No numerical data available in the source material.
Key Findings
- Corneal sensitivity is one of several factors affecting GP lens comfort, alongside lid margin sensitivity and tear film stability.
- Topical anesthesia can enhance initial GP lens tolerance by reducing corneal sensitivity and anxiety during fitting.
- GP lens wear can decrease corneal sensitivity, which may be linked to both hypoxic and mechanical mechanisms.
- Corneal sensitivity typically recovers after cessation of lens wear, indicating potential for reintroduction of GP lenses.
- Corneal nerve changes in keratoconus are complex and not fully understood, impacting sensitivity and lens tolerance.
- Post-collagen cross-linking, patients may experience temporary increases in GP lens tolerance due to reduced corneal sensitivity.
Clinical Implications
Highlight the need for ongoing assessment of corneal sensitivity in lens wearers.
Conclusion
Identify specific research questions that could further elucidate the relationship between corneal sensitivity and lens wear.
References
- Carracedo G, Martin-Gil A, Peixoto-de-Matos SC, et al., Eye Contact Lens, 2016 -- Symptoms and signs in rigid gas permeable lens wearers during adaptation period
- Nosch DS, Joos RE, Müller D, Matt SM, Clin Exp Optom, 2020 -- General pain perception sensitivity, lid margin sensitivity and gas permeable contact lens comfort
- Gill FR, Murphy PJ, Purslow C, Cont Lens Anterior Eye, 2017 -- Topical anaesthetic use prior to rigid gas permeable contact lens fitting
- Lafreniere JD, Szczesniak AM, Courtney E, et al., J Cataract Refract Surg, 2023 -- Topical analgesics for acute corneal pain: current options and emerging therapeutics
- Stapleton F, Chao C, Golebiowski B, Optom Vis Sci, 2019 -- Topical review: effects of contact lens wear on corneal, conjunctival, and lid margin sensitivity
- Spadea L, Salvatore S, Vingolo EM, ScientificWorldJournal, 2013 -- Corneal sensitivity in keratoconus: a review of the literature
- Teo AWJ, Mansoor H, Sim N, et al., J Clin Med, 2022 -- In vivo confocal microscopy evaluation in patients with keratoconus
- Ünlü M, Yüksel E, Bilgihan K, Contact Lens Spectrum, 2017 -- Effect of corneal sensitivity on GP lens tolerance
- Contact Lens Spectrum — GP Insights
- Contact Lens Spectrum — GP Insights
- Contact Lens Spectrum — GP Insights
- Contact Lens Spectrum — GP Insights
- GP Insights: Corneal Sensitivity and GP Lenses
- Corneal Ectasia Preferred Practice Pattern® - PubMed
- SCOPE research tracks increased use, performance of scleral lenses - Mayo Clinic
This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.


